黄伟伟
一、个人基本信息
黄伟伟，男，博士，副教授，细胞生物学教研室主任。2012年毕业于西北农林科技大学生命科学学院生物化学与分子生物学专业，获理学博士学位，同年进入西北农林科技大学生命科学学院生物科学系从事教学和科研工作。
二、主讲课程
主要承担《细胞生物学》、《动物发育生物学》、《细胞生物学实验》》、《显微技术综合实验》等本科生课程。
三、研究方向：
主要从事天然产物分子药理研究和核酸G-四链体及其结合蛋白功能研究。主持国家级科研项目1项、省部级项目1项、中央高校基本科研业务费多项，参与国家级科研项目多项。
四、发表论文 (#co-first author, *corresponding author)
1. 刘雪萍,黄伟伟*,李晓梅. ULK1启动子区含有抑制ULK1转录的G4结构. 中国病理生理杂志. 2021, 37(07): 1270-6.
2. 周炎鑫, 韩梦, 刘娜女, 黄伟伟*. SENP1启动子G-四链体鉴定及其作用研究. 中国生物工程杂志. 2020, 40(Z1): 92-101.
3. 马云青, 李晓梅, 刘雪萍, 韩洋洋*,黄伟伟*. 槲皮素通过G4调控癌基因表达影响肿瘤细胞增殖与凋亡. 中国细胞生物学学报. 2019, 41(12): 2319-31.
4. Han YY#, Huang WW#, Liu JK, Liu DD, Cui YY, Huang RM, Jun J*, Lei M*. Triptolide Inhibits the AR Signaling Pathway to Suppress the Proliferation of Enzalutamide Resistant Prostate Cancer Cells. Theranostics. 2017, 7 (7): 1914-27.
5. Clotaire J #, Wang YF#, Huang WW, Zhang Bin*, Lei M*. MiR-26b acts as a tumor suppressor microRNA in Prostate Cancer. Progress in Biochemistry and Biophysics. 2017, 44: 504-514.
6. Clotaire J#, Zhang B#, Wei N, Gao RF, Zhao F, Wang YF, Lei M*, Huang WW*. miR-26b inhibits autophagy by targeting ULK2 in prostate cancer cells. Biochemical and Biophysical Research Communications. 2016, 472 (1): 194-200.
7. 张斌#, 王蕴非#, 赵飞, 雷鸣*, 黄伟伟*. 雷公藤甲素诱导Hela细胞 p53 依赖的自噬和凋亡. 生物化学与生物物理进展. 2016, 43: 599-606.
8. Zhao F#, Huang WW#, Zhang Z, Mao L, Han YY, Yan J, Lei M*. Triptolide induces protective autophagy through activation of the CaMKK beta-AMPK signaling pathway in prostate cancer cells. Oncotarget. 2016, 7 (5): 5366-82.
9. Zhao F#, Huang W#, Ousman T, Zhang B, Han Y, Clotaire J, Wang C, Chang H，Luo HN, Ren XY, Lei M. Triptolide induces growth inhibition and apoptosis of human laryngocarcinoma cells by enhancing p53 activities and suppressing E6-mediated p53 degradation. PloS ONE. 2013, 8 (11): e80784.
10. Zhang J, Li QF, Huang WW, Xu XY, Zhang XL, Hui MX, Zhang MK, Zhang LG. A Vacuolar Processing Enzyme RsVPE1 Gene of Radish Is Involved in Floral Bud Abortion under Heat Stress. Int J Mol Sci. 2013, 14(7):13346-59.
11. Xu XY, Sun XL, Zhang J, Huang WW, Zhang LG*, Fang ZY*.Identification of candidate genes associated with male sterility in CMS7311 of heading Chinese cabbage ( Brassica campestris L. ssp. pekinensis ). Acta Physiologiae Plantarum , 2013, 35(11):3265-3270.
12. Huang W#, Smaldino PJ#, Zhang Q#, Miller LD, Cao P, Stadelman K, Wan M, Giri B, Lei M, Nagamine Y, Vaughn JP, Akman SA, Sui G*、 Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1. Nucleic Acids Res. 2012, 40(3):1033-49.
13. Huang W#, He T#, Chai C, Yang Y, Zheng Y, Zhang B, Liu Z, Shi C, Lei L, Li H, Zhong S, Yao L, Huang M, Lei M*.Triptolide Inhibits the Proliferation of Prostate Cancer Cells and Down-regulates SUMO-specific Protease 1 Expression. PLoS ONE, 2012, 7(5):e37693.
14. Wan M, Huang W, Kute TE, Miller LD, Zhang Q, Hatcher H, Wang J, Stovall DB, Russell GB, Cao PD, Deng Z, Wang W, Zhang Q, Lei M, Torti SV, Akman SA, Sui G*、Yin Yang 1 Plays an Essential Role in Breast Cancer and Negatively Regulates p27. Am J Pathol. 2012, 180(5):2120-33.
15. Cao P, Deng Z, Wan M, Huang W, Cramer SD, Xu J, Lei M, Sui G*、MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta. Mol Cancer. 2010, 9:108-19.
16. 雷安民, 马晓玲, 高志敏, 胡勇策, 隋进强, 黄伟伟, 昝林森, 窦忠英. 牛体细胞核移植显微操作环节的优化. 生物工程学报. 2009, 25(9): 1424-32.
17. Jia W, Yang W, Lei A, Gao Z, Yang C, Hua J, Huang W, Ma X, Wang H*, Dou Z*. A caprine chimera produced by injection of embryonic germ cells into a blastocyst. Theriogenology. 2008, 69(3):340-8.
五、联系方式
通讯地址：陕西杨凌邰城路3号西北农林科技大学南校区科研楼3408
邮 编：712100
电子邮箱：whuang0210@163.com; whuang0210@nwsuaf.edu.cn