刘杰
刘杰
一、基本信息
刘杰，男，教授，博士生导师。1999年考入东北农业大学生命科学学院生物科学本、硕、博连读（8年）专业，2007年获农学博士学位，同年进入西北农林科技大学生命科学学院生物化学与分子生物学系从事教学和科研工作。旱区作物逆境生物学国家重点实验室固定研究人员。2013.11-2014.10在美国马里兰大学生物科学与生物技术研究所（The Institute for Bioscience and Biotechnology Research）以访问学者进行合作研究。
二、研究方向
以小麦条锈病为研究对象，通过分子生物学，生物化学，植物生理学，基因组学，蛋白组学等手段，来揭示植物与病原菌互作的分子机理。主要包括：
（1）植物与病原菌互作过程中的营养转运及其调控机制。
（2）病菌效应蛋白调控寄主免疫的分子机制。
（3）泛素化修饰介导的寄主抗病机制解析。
三、开设课程
主要承担本科生《基础生物化学》、《基础生物化学实验》、《生物化学综合大实验》、《生物技术综合大实验》等课程教学工作以及研究生的《高级生物化学》课程的部分教学工作。
四、科研项目
主持国家自然科学基金面上项目（32272502）：条锈菌效应蛋白Pst15483调控糖转运子TaSTP3促进小麦感病的分子机制，54万，2023.1-2026.12.
主持“十四五”国家重点研发计划子课题（2021YFD1401001-03）：小麦条锈菌重要致病因子功能鉴定及作用机理研究，100万，2021.12-2024.11.
主持国家自然科学基金联合基金项目(U2003118)：TaRING1泛素化修饰TaPAL1抑制小麦抗条锈病的分子机理及其利用，58万，2021.1-2023.12.
主持“十三五”国家重点研发计划子课题（2016YFD0100602）：小麦抗条锈病基因克隆及其调控的分子基础，140万，2016.1-2020.12.
主持国家自然科学基金（31000078）：小麦条锈菌夏孢子芽管顶端生长过程中细胞骨架响应及相关马达蛋白功能研究，20万，2011.1-2013.12.
主持陕西省自然科学基金重点项目（2020JZ-12）：Ps3439与TaXB24互作促进小麦感条锈病的分子机理研究，10万，2020.1-2022.12.
主持陕西省留学回国人员择优资助项目: 小麦感条锈病基因TaSTP8的功能鉴定及分子机制解析, 3万，2016.1-2017.12.
主持陕西省自然科学基金面上项目（2015JM3089）：受条锈菌诱导的小麦G6PDH基因的功能鉴定及作用机理研究，3万，2015.1-2016.12.
主持中国博士后基金（20110491696）：小麦条锈菌分化相关蛋白基因DRP1的克隆及功能分析，3万，2011.1-2012.12.
五、发表论文
Xiaobo Wei, Xueling Huang, Weiling Yang, Xinran Wang, Tao Guan, Zhensheng Kang, Jie Liu*. A chloroplast-localized glucose-6-phosphate dehydrogenase positively regulates stripe rust resistance in wheat. International Journal of Molecular Sciences, 2023, 24: 459. (IF2023="6.208)
Baoyu Huai, Pu Yuan, Xiaoxuan Ma, Xiurui Zhang, Lihua Jiang, Peijing Zheng, Mohan Yao, Ziyu Chen, Liyang Chen, Qianhua Shen, Zhensheng Kang*, Jie Liu*. Sugar transporter TaSTP3 activation by TaWRKY19/61/82 enhances stripe rust susceptibility in wheat. New Phytologist, 2022, 236(1): 266-282. (IF2022="10.323)
Jie Liu, Mengxue Liu, Liqiang Tan, Baoyu Huai, Xianfeng Ma, Qinglin Pan, Peijing Zheng, Yingqiang Wen, Qiong Zhang, Qi Zhao, Zhensheng Kang*, Shunyuan Xiao*. AtSTP8, an endoplasmic reticulum-localised monosaccharide transporter from Arabidopsis, is recruited to the extrahaustorial membrane during powdery mildew infection. New Phytologist, 2021, 230: 2404-2419. (IF2021="10.151)
Pu Yuan, Wenhao Qian, Lihua Jiang, Conghui Jia, Xiaoxuan Ma, Zhensheng Kang*, Jie Liu*. A secreted catalase contributes to Puccinia striiformis resistance to host-derived oxidative stress. Stress Biology, 2021, 1: 22.
Qing Chang, Xiaohong Lin, Mohan Yao, Peng Liu, Jia Guo, Lili Huang, Ralf T. Voegele, Zhensheng Kang*, Jie Liu*. Hexose transporter PsHXT1-mediated sugar uptake is required for pathogenicity of wheat stripe rust. Plant Biotechnology Journal, 2020, 18:2367-2369. (IF2020="8.154)
Peijing Zheng, Liyang Chen, Suye Zhong, Xiaobo Wei, Qi Zhao, Qinglin Pan, Zhensheng Kang*, Jie Liu*. A Cu-only superoxide dismutase from stripe rust fungi functions as a virulence factor deployed for counter defense against host-derived oxidative stress. Environmental Microbiology, 2020, 22(12): 5309-5326. (IF2020="4.933)
Baoyu Huai, Qian Yang, Xiaobo Wei, Qinglin Pan, Zhensheng Kang*, Jie Liu*. TaSTP13 contributes to wheat susceptibility to stripe rust possibly by increasing cytoplasmic hexose concentration. BMC Plant Biology, 2020, 20(1): 49. (IF2020="3.67)
Baoyu Huai, Qian Yang, Yingrui Qian, Wenhao Qian, Zhensheng Kang, Jie Liu*. ABA-induced sugar transporter TaSTP6 promotes wheat susceptibility to stripe rust. Plant Physiology, 2019, 181(3): 1328-1343. (IF2019="6.305, F1000Prime推荐).
Dan Li, Lijing Pang, Pu Yuan, Peijing Zheng, Baoyu Huai, Mohan Yao, Zhensheng Kang*, Jie Liu*. A novel citrate synthase isoform contributes infection and stress resistance of the stripe rust fungus. Environmental Microbiology, 2018, 20(11), 4037–4050. (IF2018="4.974)
Qing Chang#, Jie Liu# (co-first author), Xiaohong Lin, Shoujun Hu, Yang Yang, Dan Li, Liyang Chen, Baoyu Huai, Lili Huang, Ralf Voegele, Zhensheng Kang*. A unique invertase is important for sugar absorption of an obligate biotrophic pathogen during infection. New Phytologist, 2017, 215(4): 1548-1561. (IF2017="7.33)
Jie Liu, Tao Guan, Peijing Zheng, Liyang Chen, Yang Yang, Baoyu Huai, Dan Li, Qing Chang, Lili Huang, Zhensheng Kang*. An extracellular Zn-only superoxide dismutase from Puccinia striiformis confers enhanced resistance to host-derived oxidative stress. Environmental Microbiology, 2016, 18(11): 4118-4135. (IF2016="5.932)
Jie Liu, Lina Han, Baoyu Huai, Peijing Zheng, Qing Chang, Tao Guan, Dan Li, Lili Huang, Zhensheng Kang*. Down-regulation of a wheat alkaline/neutral invertase correlates with reduced host susceptibility to wheat sripe rust caused by Puccinia striiformis . Journal of Experimental Botany, 2015, 66(22):7325-7338. (IF2015="5.526)
Jie Liu, Qiuling Wang, Qing Chang, Lina Han, Guoliang Pei, Yueqing Xue, Lumeng Jia, Kun Zhang, Yuanyuan Duan, Zhensheng Kang*. Isocitrate lyase is required for urediniospore germination of Puccinia striiformis f. sp. tritici . Mol Biol Rep, 2014, 41:7797-7806. (IF2014="1.958)
Jie Liu, Lina Han, Qiong Zhang, Qiuling Wang, Qing Chang, Hua Zhuang, Jia Liu, Man Li, Dan Yu, Zhensheng Kang*. Cloning and molecular characterization of a myosin light chain gene from Puccinia striiformis f. sp. tritici . World J Microb Biot, 2014, 30: 631-637. (IF2014="1.353)
Jie Liu, Qiong Zhang, Qing Chang, Qiuling Wang, Lina Han, Jia Liu, Man Li, Hua Zhuang, Zhensheng Kang. Cloning and characterization of a dynein light chain gene from Puccinia striiformis f. sp. tritici . J Basic Microb, 2014, 54, S32-S41. (IF2014="1.822)
Jie Liu, Qiong Zhang, Qing Chang, Hua Zhuang, Lili Huang, Zhensheng Kang*. Cloning and characterization of the actin gene from Puccinia striiformis f. sp. tritici . World J Microb Biot, 2012, 28:2331-2339. (IF2012="1.532)
Jie Liu*, Chunhong Fang, Yanlong Jiang, Ruoyu Yan. Characterization of a hemolysin gene ytjA from Bacillus subtilis. Curr Microbiol, 2009, 58(6): 642-647. (IF2009="1.33)
Jie Liu*, Qiong Zhang, Chunhong Fang. Deletion of the yhdT gene of Bacillus subtilis and its influence on hemolysis. Afr J Biotechnol, 2010, 9(39): 6470-7476. (IF2010="0.565)
Qing Chang, Jie Liu*, Qiuling Wang, Lina Han, Jia Liu, Man Li, Lili Huang, Jiarong Yang, Zhensheng Kang*. The effect of Puccinia striiformis f. sp. tritici on the levels of water-soluble carbohydrates and the photosynthetic rate in wheat leaves. Physiol Mol Plant P, 2013, 84: 131-137. (IF2013="1.506)
Zheng W, Huang L, Huang J, Wang X, Chen X, Zhao J, Guo J, Zhuang H, Qiu C, Liu J, Liu H, Huang X, Pei G, Zhan G, Tang C, Cheng Y, Liu M, Zhang J, Zhao Z, Zhang S, Han Q, Han D, Zhang H, Zhao J, Gao X, Wang J, Ni P, Dong W, Yang L, Yang H, Xu JR, Zhang G, Kang Z. High genome heterozygosity and endemic genetic recombination in the wheat stripe rust fungus. Nat Commun. 2013, 4:2673. (IF2013="10.015)
六、联系方式
办公室：西北农林科技大学生命科学学院D306室
实验室：西北农林科技大学南校区旱区作物逆境生物学国家重点实验1111室
E-mail: neauliu@sina.com or liujie2003@hotmail.com